Immuno-oncology ELISA Kits and Multiplex Immunoassays - UK (2024)

Invitrogen ProcartaPlex Immuno-Oncology Checkpoint Panels allow for the simultaneous detection of up to 38 soluble immune checkpoint molecules and help provide a more comprehensive picture of cancer immunity.

Several checkpoint inhibitors were detected in tumor tissue extracts from mouse using the ProcartaPlex Mouse Immuno-Oncology Checkpoint Panel, 4plex and ProcartaPlex Mouse Immuno-Oncology Checkpoint Panel 2, 7plex (Figure 3). We have also measured checkpoint markers in melanoma patient samples using the ProcartaPlex Human Immuno-Oncology Checkpoint Panel 1, 14plex and ProcartaPlex Human Immuno-Oncology Checkpoint Panel 2, 14plex (Figure 4).

Our Immuno-Oncology Checkpoint panels have been specifically designed and optimized for cerebral spinal fluid, serum, and plasma samples (Table 3). Use preconfigured panels below or select from single targets to create your own custom panel to study either human or mouse immune checkpoint biomarkers.

ProcartaPlex Panel Configurator

Learn more aboutProcartaPlex multiplex immunoassays


Table 3. Preconfigured ProcartaPlex multiplex immunoassay panels for immuno-oncology.

QuantiGene RNA gene expression assays provide a fast and high-throughput solution for multiplexed gene expression quantitation, with simultaneous measurement of up to 80 genes of interest in a single well of a 96- or 384-well plate. The QuantiGene Plex assay is based on hybridization and incorporates branched DNA (bDNA) technology, which uses signal amplification rather than target amplification for direct measurement of RNA transcripts. The assay is run on the Luminex platform, has a simple workflow, and does not require RNA purification. These features allow the user to merge the QuantiGene workflow for gene expression profiling with the ProcartaPlex workflow for protein quantitation using the same sample (Figure 5).

Learn more aboutQuantiGene RNA Assays for Gene Expression Profiling

Read our publication: Multiplexing protein and gene level measurements on a single Luminex platform. Methods, 2019. 158: 27-32.

Researchers can now gain deeper insights through the preconfigured panels such as theQuantiGene Plex Human Immune Response Panel, 80-plex, which simultaneously analyzes 80 cytokine, chemokine, and growth factor targets. These targets are complementary and correlate to theProcartaPlex Human Immune Response Panel, 80plexallowing maximum data per sample using the same instrument(Figure 6). Full data, along with the target list and correlation analysis can be foundhere.

Additional panels are also available for curated research into immune profiling and cancer biomarkers across human and mice samples(Table 4).

Table 4. Immune Response and Cancer Profiling Gene Expression Panels.

Product nameSizeCat. No.

QuantiGene Plex Human Immune Response Panel, 80-plex

Targets: CCL1, CCL13, CCL17 ,CCL19, CCL2, CCL21, CCL22, CCL23, CCL24, CCL25, CCL26, CCL4, CCL7, CCL8, CD40LG, CSF1, CSF2, CSF3, CX3CL1,CXCL1, CXCL11, CXCL13, CXCL2, CXCL5, CXCL6, CXCL9, CXCR3, FGF2, GZMA, GZMB, HGF, IFNA1, IFNG, IL10, IL12A, IL12B, IL13, IL15, IL16, IL17A, IL18, IL1A, IL1B, IL2, IL20, IL21, IL22, IL23A, IL27, IL2RA, IL3, IL31, IL34, IL37, IL4, IL5, IL6, IL8, IL9, KITLG, LGALS3, LIF, LTA, MIF, NGF, PTX3, TNF, TNFRSF12A, TNFRSF1B, TNFRSF8, TNFSF10, TNFSF13, TNFSF13B, TREM1, TSLP, VEGFA, PPIB, HPRT1, GAPDH, GUSB

1 plate

QGP-180-10080

3 plates

QGP-280-10080

10 plates

QGP-380-10080

QuantiGene Plex Mouse Immune Response Panel, 80-plex

Targets: Il2ra, Il2, Il6, Ifng, Tnf, Il5, Il1a, Csf2, Il4, Il10, Il18, Vegfa, Il17a, Il1b, Il12a, Ccl2, Ccl7, Ccl11, Ccl5, Cxcl11, Il6ra, Ccl3, Ccl4, Il13, Il23a, Cxcr3, Il22, Il15, Il27, Il33, Ifna1, Il28a, Il31, Cxcl1, Cxcl2, Csf3, Il3, Lep, Tnfsf11, Csf1, Lif, Il9, Btc, Cxcl5, Il25, Il1rl1, Il19, Cd27, Kdr, Ccl19, Cxcl16, Il16, Ccl22, Ccl12, Gzmb, Ccl27a, Ccl24, Ccl17, Ccl25, Cxcl13, Il7r, Il7, Tslp, Tnfsf13b, Il12b, Il21, Gzma, Cd274, Ctla4, Cxcl9, Havcr2, Lag3, Ifna2, Ifnb1, Hgf, Tnfrsf12a, Ppib, Hprt, Gapdh, Gusb

1 plate

QGP-180-20064

3 plates

QGP-280-20064

10 plates

QGP-380-20064

QuantiGene Plex Human PanCancer Panel, 80-plex

Targets: AGER, ARG1, AXL, BDNF, BTLA, CALR, CD27, CD274, CD276, CD28, CD36, CD47, CD48, CD80, CD96, CDH1, CSF3, CTLA4, CXCL8, DKK1, EGF, EPCAM, FGF2, GAPDH, GAS6, GPC1, GUSB, HAVCR2, HGF, HMGB1, HPRT1, HSP90AA1, HSPA4, HSPB2, HSPD1, ICOSLG, IDO1, IGF2, KITLG, LAG3, LGALS9, LIF, MBL2, MDK, MERTK, MICA, MICB, NCR3LG1, NECTIN2, NGF, NT5E, NTRK2, OLR1, PDCD1LG2, PECAM1, PGF, PLAUR, PPIB, PRF1, PVR, RAET1E, S100A8, S100A9, SERPINE1, SIGLEC7, SIGLEC9, SPARC, SPATA2, TIMD4, TNFRSF14, TNFRSF18, TNFRSF4, TNFRSF9, TRIM8, TYRO3, ULBP1, ULBP3, VEGFA, VEGFD, VSIR

1 plate

QGP-180-HUPANCANCER

3 plates

QGP-280-HUPANCANCER

10 plates

QGP-380-HUPANCANCER

QuantiGene Plex Mouse PanCancer Panel, 80-plex

Targets: Ager, Arg1, Axl, Bdnf, Btla, Calr, Cd27, Cd274, Cd276, Cd28, Cd36, Cd47, Cd48, Cd80, Cd96, Cdh1, Csf3, Ctla4, Cxcl1, Dkk1, Egf, Epcam, Fgf2, Gapdh, Gas6, Gpc1, Gusb, Havcr2, Hgf, Hmgb1, Hprt, Hsp90Aa1, Hspa4, Hspb2, Hspd1, Icosl, Ido1, Igf2, Inhca , Kitl, Lag3, Lgals9, Lif, Mbl2, Mdk, Mertk, Mill2, Ncr1, Nectin2, Ngf, Nt5E, Ntrk2, Olr1, Pdcd1Lg2, Pecam1, Pgf, Plaur, Ppib, Prf1, Pvr, Raet1E, S100A8, S100A9, Serpine1, Siglece, Siglech, Sparc, Spata2, Timd4, Tnfrsf14 , Tnfrsf18, Tnfrsf4, Tnfrsf9, Trim8, Tyro3, Ulbp1, Ulbp3, Vegfa, Vegfd, Vsir

1 plate

QGP-180-MSPANCANCER

3 plates

QGP-280-MSPANCANCER

10 plates

QGP-380-MSPANCANCER

Immuno-oncology ELISA Kits and Multiplex Immunoassays - UK (2024)

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